The treatment of the infectious and other diseases via the inhibition of their causative agents involves the induction of the immune system through the process of vaccination. An effective and successful outcome with the vaccines is achieved only when they are able to raise the antigen specific acquired responses of the immune system that involves memory.
The major mediators of this form of immunity are the lymphocytes. The B lymphocytes generally deal with the pathogens which are external through the formation of antibodies while the internal pathogens are tackled by the T lymphocytes that involve cytokine producing inflammatory responses.
Besides the classical way of the application of vaccination during which the acquired immunity against the target antigen is stimulated, there is a great deal of interest among the individuals regarding the significance of innate immunity. This form of immunity has been found to be involved with the beneficial microflora of the hosts or the administration of the probiotics. Infact, it has now been established that the early exposure to the gut microbiota in the lives of the neonatals is absolutely necessary for the development of mucosal immunity. Therefore, there are good reasons to believe that the probiotics can be used as effective means of vaccine delivery. [Read more…]